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Data driven and biophysical insights into the regulation of trafficking vesicles by extracellular matrix stiffness

Biomechanical signals from remodeled extracellular matrix (ECM) promote tumor progression. Here, we show that cell-matrix and cell-cell communication may be inherently linked and tuned through mechanisms of mechanosensitive biogenesis of trafficking vesicles. Pan-cancer analysis of cancer cells'...

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Detalles Bibliográficos
Autores principales: Parihar, Kshitiz, Nukpezah, Jonathan, Iwamoto, Daniel V., Janmey, Paul A., Radhakrishnan, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293776/
https://www.ncbi.nlm.nih.gov/pubmed/35865140
http://dx.doi.org/10.1016/j.isci.2022.104721