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RNA editing enzyme ADAR1 controls miR-381-3p-mediated expression of multidrug resistance protein MRP4 via regulation of circRNA in human renal cells

Multidrug resistance–associated protein 4 (MRP4), a member of the C subfamily of ATP-binding cassette transporters, is highly expressed in the kidneys of mammals and is responsible for renal elimination of numerous drugs. Adenosine deaminase acting on RNA 1 (ADAR1) has been reported to regulate gene...

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Detalles Bibliográficos
Autores principales: Omata, Yuji, Okawa, Maseri, Haraguchi, Mai, Tsuruta, Akito, Matsunaga, Naoya, Koyanagi, Satoru, Ohdo, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293778/
https://www.ncbi.nlm.nih.gov/pubmed/35753353
http://dx.doi.org/10.1016/j.jbc.2022.102184