Cargando…

Hairy cell leukemia: a specific 17-gene expression signature points to new targets for therapy

BACKGROUND: Hairy cell leukemia (HCL) is a rare chronic B cell malignancy, characterized by infiltration of bone marrow, blood and spleen by typical “hairy cells” that bear the BRAFV600E mutation. However, in addition to the intrinsic activation of the MAP kinase pathway as a consequence of the BRAF...

Descripción completa

Detalles Bibliográficos
Autores principales: Maitre, Elsa, Cornet, Edouard, Debliquis, Agathe, Drenou, Bernard, Gravey, François, Chollet, Didier, Cheze, Stephane, Docquier, Mylène, Troussard, Xavier, Matthes, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293816/
https://www.ncbi.nlm.nih.gov/pubmed/35476232
http://dx.doi.org/10.1007/s00432-022-04010-4