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COPD lung studies of Nrf2 expression and the effects of Nrf2 activators

BACKGROUND: Nrf2 regulates cellular antioxidant defence in lung cells, including epithelial cells and alveolar macrophages (AM). The Nrf2/Keap-1 pathway can be modulated by activators with different modes of action; electrophilic compounds and protein–protein interaction (PPI) inhibitors. We assesse...

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Detalles Bibliográficos
Autores principales: Li, Jian, Baker, James, Higham, Andrew, Shah, Rajesh, Montero-Fernandez, Angeles, Murray, Clare, Cooper, Nicky, Lucas, Cathy, Fox, Craig, Singh, Dave, Lea, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293829/
https://www.ncbi.nlm.nih.gov/pubmed/35441963
http://dx.doi.org/10.1007/s10787-022-00967-3