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Autophagy Dysfunction in ALS: from Transport to Protein Degradation

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting upper and lower motor neurons (MNs). Since the identification of the first ALS mutation in 1993, more than 40 genes have been associated with the disorder. The most frequent genetic causes of ALS are represented by mu...

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Detalles Bibliográficos
Autores principales: Cozzi, Marta, Ferrari, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293831/
https://www.ncbi.nlm.nih.gov/pubmed/35708843
http://dx.doi.org/10.1007/s12031-022-02029-3