Simultaneous quantification of eight hemoglobin adducts of genotoxic substances by isotope-dilution UHPLC-MS/MS

Various genotoxic carcinogens ubiquitously present in the human environment or respective reactive metabolites form adducts in DNA and proteins, which can be used as biomarkers of internal exposure. For example, the mass spectrometric determination of Val adducts at the N-termini of hemoglobin (Hb)...

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Detalles Bibliográficos
Autores principales: Gauch, Fabian, Abraham, Klaus, Monien, Bernhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293867/
https://www.ncbi.nlm.nih.gov/pubmed/35655100
http://dx.doi.org/10.1007/s00216-022-04143-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293867/
https://www.ncbi.nlm.nih.gov/pubmed/35655100
http://dx.doi.org/10.1007/s00216-022-04143-y

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