Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5

Physical mechanical stimulation can maintain and even increase bone mass. Here, we report an important role of osteocytic integrin α5 in regulating the anabolic response of bone to mechanical loading using an Itga5 conditional gene knockout (cKO) mouse model. Integrin α5 gene deletion increased apop...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Dezhi, Hua, Rui, Riquelme, Manuel A., Cheng, Hongyun, Guda, Teja, Xu, Huiyun, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293884/
https://www.ncbi.nlm.nih.gov/pubmed/35851577
http://dx.doi.org/10.1038/s41413-022-00222-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293884/
https://www.ncbi.nlm.nih.gov/pubmed/35851577
http://dx.doi.org/10.1038/s41413-022-00222-z

Ejemplares similares