Cargando…
Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5
Physical mechanical stimulation can maintain and even increase bone mass. Here, we report an important role of osteocytic integrin α5 in regulating the anabolic response of bone to mechanical loading using an Itga5 conditional gene knockout (cKO) mouse model. Integrin α5 gene deletion increased apop...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293884/ https://www.ncbi.nlm.nih.gov/pubmed/35851577 http://dx.doi.org/10.1038/s41413-022-00222-z |