Structural basis for the activation and ligand recognition of the human oxytocin receptor

The small cyclic neuropeptide hormone oxytocin (OT) and its cognate receptor play a central role in the regulation of social behaviour and sexual reproduction. Here we report the single-particle cryo-electron microscopy structure of the active oxytocin receptor (OTR) in complex with its cognate liga...

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Detalles Bibliográficos
Autores principales: Waltenspühl, Yann, Ehrenmann, Janosch, Vacca, Santiago, Thom, Cristian, Medalia, Ohad, Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293896/
https://www.ncbi.nlm.nih.gov/pubmed/35851571
http://dx.doi.org/10.1038/s41467-022-31325-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293896/
https://www.ncbi.nlm.nih.gov/pubmed/35851571
http://dx.doi.org/10.1038/s41467-022-31325-0

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