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Structural basis for the activation and ligand recognition of the human oxytocin receptor

The small cyclic neuropeptide hormone oxytocin (OT) and its cognate receptor play a central role in the regulation of social behaviour and sexual reproduction. Here we report the single-particle cryo-electron microscopy structure of the active oxytocin receptor (OTR) in complex with its cognate liga...

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Detalles Bibliográficos
Autores principales:	Waltenspühl, Yann, Ehrenmann, Janosch, Vacca, Santiago, Thom, Cristian, Medalia, Ohad, Plückthun, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293896/ https://www.ncbi.nlm.nih.gov/pubmed/35851571 http://dx.doi.org/10.1038/s41467-022-31325-0

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