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The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons

Selective Serotonin Reuptake Inhibitors (SSRIs) may hold therapeutic benefits for people with Alzheimer’s disease (AD). SSRIs may perturb AD progression, or the conversion from MCI to AD, via increased neurogenesis, reduced oxidative stress and/or favourable Amyloid-β Precursor Protein (AβPP) proces...

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Detalles Bibliográficos
Autores principales: Elsworthy, R. J., Crowe, J. A., King, M. C., Dunleavy, C., Fisher, E., Ludlam, A., Parri, H. R., Hill, E. J., Aldred, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293911/
https://www.ncbi.nlm.nih.gov/pubmed/35851379
http://dx.doi.org/10.1038/s41398-022-02050-5