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Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN

Tumor volume increases continuously in the advanced stage, and aside from the self-renewal of tumor cells, whether the oncogenic transformation of surrounding normal cells is involved in this process is currently unclear. Here, we show that oral squamous cell carcinoma (OSCC)-derived small extracell...

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Detalles Bibliográficos
Autores principales: Liang, Weilian, Chen, Yang, Liu, Hanzhe, Zhao, Hui, Luo, Tingting, Tang, Hokeung, Zhou, Xiaocheng, Jiang, Erhui, Shao, Zhe, Liu, Ke, Shang, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293927/
https://www.ncbi.nlm.nih.gov/pubmed/35851058
http://dx.doi.org/10.1038/s41368-022-00192-2