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Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells

Cellular senescence and cell competition are important tumor suppression mechanisms that restrain cells with oncogenic mutations at the initial stage of cancer development. However, the link between cellular senescence and cell competition remains unclear. Senescent cells accumulated during the in v...

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Detalles Bibliográficos
Autores principales: Igarashi, Nanase, Miyata, Kenichi, Loo, Tze Mun, Chiba, Masatomo, Hanyu, Aki, Nishio, Mika, Kawasaki, Hiroko, Zheng, Hao, Toyokuni, Shinya, Kon, Shunsuke, Moriyama, Keiji, Fujita, Yasuyuki, Takahashi, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293948/
https://www.ncbi.nlm.nih.gov/pubmed/35851277
http://dx.doi.org/10.1038/s41467-022-31642-4