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Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload
Heart failure (HF) is the inability of the heart to pump blood sufficiently to meet the metabolic demands of the body. HF with reduced systolic function is characterized by cardiac hypertrophy, ventricular fibrosis and remodeling, and decreased cardiac contractility, leading to cardiac functional im...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293976/ https://www.ncbi.nlm.nih.gov/pubmed/35851833 http://dx.doi.org/10.1038/s41598-022-16506-7 |