Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload

Heart failure (HF) is the inability of the heart to pump blood sufficiently to meet the metabolic demands of the body. HF with reduced systolic function is characterized by cardiac hypertrophy, ventricular fibrosis and remodeling, and decreased cardiac contractility, leading to cardiac functional im...

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Detalles Bibliográficos
Autores principales: Guo, Angela H., Baliira, Rachael, Skinner, Mary E., Kumar, Surinder, Andren, Anthony, Zhang, Li, Goldsmith, Robert S., Michan, Shaday, Davis, Norma J., Maccani, Merissa W., Day, Sharlene M., Sinclair, David A., Brody, Matthew J., Lyssiotis, Costas A., Stein, Adam B., Lombard, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293976/
https://www.ncbi.nlm.nih.gov/pubmed/35851833
http://dx.doi.org/10.1038/s41598-022-16506-7

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