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NNMT promotes the progression of intrahepatic cholangiocarcinoma by regulating aerobic glycolysis via the EGFR-STAT3 axis

Nicotinamide N-methyltransferase (NNMT), a member of the N-methyltransferase family, plays an important role in tumorigenesis. However, its expression and biological functions in intrahepatic cholangiocarcinoma (iCCA) remain to be established. In our study, we identified NNMT as an oncogene in iCCA...

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Detalles Bibliográficos
Autores principales: Lu, Shounan, Ke, Shanjia, Wang, Chaoqun, Xu, Yanan, Li, Zihao, Song, Keda, Bai, Miaoyu, Zhou, Menghua, Yu, Hongjun, Yin, Bing, Li, Xinglong, Feng, Zhigang, Hua, Yongliang, Pan, Shangha, Jiang, Hongchi, Li, Linqiang, Wu, Yaohua, Ma, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293979/
https://www.ncbi.nlm.nih.gov/pubmed/35851575
http://dx.doi.org/10.1038/s41389-022-00415-5