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NNMT promotes the progression of intrahepatic cholangiocarcinoma by regulating aerobic glycolysis via the EGFR-STAT3 axis
Nicotinamide N-methyltransferase (NNMT), a member of the N-methyltransferase family, plays an important role in tumorigenesis. However, its expression and biological functions in intrahepatic cholangiocarcinoma (iCCA) remain to be established. In our study, we identified NNMT as an oncogene in iCCA...
Autores principales: | Lu, Shounan, Ke, Shanjia, Wang, Chaoqun, Xu, Yanan, Li, Zihao, Song, Keda, Bai, Miaoyu, Zhou, Menghua, Yu, Hongjun, Yin, Bing, Li, Xinglong, Feng, Zhigang, Hua, Yongliang, Pan, Shangha, Jiang, Hongchi, Li, Linqiang, Wu, Yaohua, Ma, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293979/ https://www.ncbi.nlm.nih.gov/pubmed/35851575 http://dx.doi.org/10.1038/s41389-022-00415-5 |
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