Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children

T-follicular helper (Tfh) cells are key drivers of antibodies that protect from malaria. However, little is known regarding the host and parasite factors that influence Tfh and functional antibody development. Here, we use samples from a large cross-sectional study of children residing in an area of...

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Detalles Bibliográficos
Autores principales: Chan, Jo-Anne, Loughland, Jessica R., de la Parte, Lauren, Okano, Satomi, Ssewanyana, Isaac, Nalubega, Mayimuna, Nankya, Felistas, Musinguzi, Kenneth, Rek, John, Arinaitwe, Emmanuel, Tipping, Peta, Bourke, Peter, Andrew, Dean, Dooley, Nicholas, SheelaNair, Arya, Wines, Bruce D., Hogarth, P. Mark, Beeson, James G., Greenhouse, Bryan, Dorsey, Grant, Kamya, Moses, Hartel, Gunter, Minigo, Gabriela, Feeney, Margaret, Jagannathan, Prasanna, Boyle, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293980/
https://www.ncbi.nlm.nih.gov/pubmed/35851033
http://dx.doi.org/10.1038/s41467-022-31880-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293980/
https://www.ncbi.nlm.nih.gov/pubmed/35851033
http://dx.doi.org/10.1038/s41467-022-31880-6

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