Cytochrome B5 type A alleviates HCC metastasis via regulating STOML2 related autophagy and promoting sensitivity to ruxolitinib

The incidence of hepatocellular carcinoma (HCC) is increasing in the world. However, its role and underlying molecular mechanism in HCC progression remain unclear. We found that CYB5A plays a key role in HCC metastasis by inhibiting the JAK1/STAT3 pathway through binding to STOML2. CYB5A combined wi...

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Detalles Bibliográficos
Autores principales: Guo, Hongrui, Liang, Shuhang, Wang, Yan, Zhou, Shuo, Yin, Dalong, Zhang, Shugeng, Wang, Jizhou, Wu, Dehai, Ma, Kun, Liu, Yufeng, Sun, Linmao, Ji, Changyong, Li, Xianying, Zhou, Huanran, Yang, Guangchao, Guo, Xinyu, Cui, Tianming, Li, Zihao, Liu, Yao, Wang, Jiabei, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293983/
https://www.ncbi.nlm.nih.gov/pubmed/35851063
http://dx.doi.org/10.1038/s41419-022-05053-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293983/
https://www.ncbi.nlm.nih.gov/pubmed/35851063
http://dx.doi.org/10.1038/s41419-022-05053-8

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