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A strategy to quantify myofibroblast activation on a continuous spectrum

Myofibroblasts are a highly secretory and contractile cell phenotype that are predominant in wound healing and fibrotic disease. Traditionally, myofibroblasts are identified by the de novo expression and assembly of alpha-smooth muscle actin stress fibers, leading to a binary classification: “activa...

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Detalles Bibliográficos
Autores principales: Hillsley, Alexander, Santoso, Matthew S., Engels, Sean M., Halwachs, Kathleen N., Contreras, Lydia M., Rosales, Adrianne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293987/
https://www.ncbi.nlm.nih.gov/pubmed/35851602
http://dx.doi.org/10.1038/s41598-022-16158-7