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A strategy to quantify myofibroblast activation on a continuous spectrum
Myofibroblasts are a highly secretory and contractile cell phenotype that are predominant in wound healing and fibrotic disease. Traditionally, myofibroblasts are identified by the de novo expression and assembly of alpha-smooth muscle actin stress fibers, leading to a binary classification: “activa...
Autores principales: | Hillsley, Alexander, Santoso, Matthew S., Engels, Sean M., Halwachs, Kathleen N., Contreras, Lydia M., Rosales, Adrianne M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293987/ https://www.ncbi.nlm.nih.gov/pubmed/35851602 http://dx.doi.org/10.1038/s41598-022-16158-7 |
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