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Orexin neurons inhibit sleep to promote arousal

Humans and animals lacking orexin neurons exhibit daytime sleepiness, sleep attacks, and state instability. While the circuit basis by which orexin neurons contribute to consolidated wakefulness remains unclear, existing models posit that orexin neurons provide their wake-stabilizing influence by ex...

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Detalles Bibliográficos
Autores principales: De Luca, Roberto, Nardone, Stefano, Grace, Kevin P., Venner, Anne, Cristofolini, Michela, Bandaru, Sathyajit S., Sohn, Lauren T., Kong, Dong, Mochizuki, Takatoshi, Viberti, Bianca, Zhu, Lin, Zito, Antonino, Scammell, Thomas E., Saper, Clifford B., Lowell, Bradford B., Fuller, Patrick M., Arrigoni, Elda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293990/
https://www.ncbi.nlm.nih.gov/pubmed/35851580
http://dx.doi.org/10.1038/s41467-022-31591-y