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Domain-level epitope mapping of polyclonal antibodies against HER-1 and HER-2 receptors using phage display technology

HER-1 and HER-2 are tumor-associated antigens overexpressed in several epithelial tumors, and successfully targeted by therapeutic approaches against cancer. Vaccination with their recombinant extracellular domains has had encouraging results in the pre-clinical setting. As complex humoral responses...

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Detalles Bibliográficos
Autores principales: Pérez-Martínez, Dayana, Infante, Yanelys Cabrera, Ramírez, Belinda Sánchez, Rojas, Gertrudis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293994/
https://www.ncbi.nlm.nih.gov/pubmed/35851313
http://dx.doi.org/10.1038/s41598-022-16411-z