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Domain-level epitope mapping of polyclonal antibodies against HER-1 and HER-2 receptors using phage display technology
HER-1 and HER-2 are tumor-associated antigens overexpressed in several epithelial tumors, and successfully targeted by therapeutic approaches against cancer. Vaccination with their recombinant extracellular domains has had encouraging results in the pre-clinical setting. As complex humoral responses...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9293994/ https://www.ncbi.nlm.nih.gov/pubmed/35851313 http://dx.doi.org/10.1038/s41598-022-16411-z |