A multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility

BACKGROUND: Over 200 genetic loci have been associated with multiple sclerosis (MS) explaining ~ 50% of its heritability, suggesting that additional mechanisms may account for the “missing heritability” phenomenon. OBJECTIVE: To analyze a large cohort of Italian individuals to identify markers assoc...

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Detalles Bibliográficos
Autores principales: Sorosina, Melissa, Barizzone, Nadia, Clarelli, Ferdinando, Anand, Santosh, Lupoli, Sara, Salvi, Erika, Mangano, Eleonora, Bordoni, Roberta, Roostaei, Tina, Mascia, Elisabetta, Zuccalà, Miriam, Vecchio, Domizia, Cavalla, Paola, Santoro, Silvia, Ferrè, Laura, Zollo, Alen, Barlassina, Cristina, Cusi, Daniele, Martinelli, Vittorio, Comi, Giancarlo, Leone, Maurizio, Filippi, Massimo, Patsopoulos, Nikolaos A., De Jager, Philip L., De Bellis, Gianluca, Esposito, Federica, D’Alfonso, Sandra, Martinelli Boneschi, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294010/
https://www.ncbi.nlm.nih.gov/pubmed/35545683
http://dx.doi.org/10.1007/s00415-022-11109-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294010/
https://www.ncbi.nlm.nih.gov/pubmed/35545683
http://dx.doi.org/10.1007/s00415-022-11109-8

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