Crystallographic mining of ASK1 regulators to unravel the intricate PPI interfaces for the discovery of small molecule

Protein seldom performs biological activities in isolation. Understanding the protein–protein interactions’ physical rewiring in response to pathological conditions or pathogen infection can help advance our comprehension of disease etiology, progression, and pathogenesis, which allow us to explore...

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Detalles Bibliográficos
Autores principales: Agrahari, Ashish Kumar, Dikshit, Madhu, Asthana, Shailendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294202/
https://www.ncbi.nlm.nih.gov/pubmed/35891784
http://dx.doi.org/10.1016/j.csbj.2022.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294202/
https://www.ncbi.nlm.nih.gov/pubmed/35891784
http://dx.doi.org/10.1016/j.csbj.2022.07.008

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