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Crystallographic mining of ASK1 regulators to unravel the intricate PPI interfaces for the discovery of small molecule
Protein seldom performs biological activities in isolation. Understanding the protein–protein interactions’ physical rewiring in response to pathological conditions or pathogen infection can help advance our comprehension of disease etiology, progression, and pathogenesis, which allow us to explore...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294202/ https://www.ncbi.nlm.nih.gov/pubmed/35891784 http://dx.doi.org/10.1016/j.csbj.2022.07.008 |