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Cardioprotective Effect of Paeonol on Chronic Heart Failure Induced by Doxorubicin via Regulating the miR-21-5p/S-Phase Kinase-Associated Protein 2 Axis

BACKGROUND: This study primarily explored the role of paeonol in doxorubicin (DOX)-induced chronic heart failure (CHF), considering the cardioprotective effect of paeonol on an epirubicin-induced cardiac injury. METHODS: DOX-induced CHF-modeled rats were treated with paeonol. Cardiac function and my...

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Detalles Bibliográficos
Autores principales: Chen, Cong, Liu, Shuhong, Cao, Gaozhen, Hu, Yang, Wang, Run, Wu, Min, Liu, Mingya, Yiu, Kai Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294229/
https://www.ncbi.nlm.nih.gov/pubmed/35865382
http://dx.doi.org/10.3389/fcvm.2022.695004