gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII

The protein gC1qR/C1qBP/HABP-1 plays an essential role in mitochondrial biogenesis, but becomes localized at the cellular surface in numerous pathophysiological states. When this occurs on endothelial cells, surface-exposed gC1qR activates the classical pathway of complement. It also promotes assemb...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Vontz, Alexander J., Kallenberger, Ethan M., Xu, Xin, Ploscariu, Nicoleta T., Ramyar, Kasra X., Garcia, Brandon L., Ghebrehiwet, Berhane, Geisbrecht, Brian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294231/
https://www.ncbi.nlm.nih.gov/pubmed/35865516
http://dx.doi.org/10.3389/fimmu.2022.887742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294231/
https://www.ncbi.nlm.nih.gov/pubmed/35865516
http://dx.doi.org/10.3389/fimmu.2022.887742

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