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Combined transgene immortalized urothelial cells capable of reprogramming and hepatic differentiation

Human primary cells, including urine-derived cells (UCs), are an excellent source for generation of pluripotent stem cells (iPSCs) to model disease. However, replicative senescence starts early and shortens the time window for generation of iPSCs. We addressed the question whether combinations of tr...

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Detalles Bibliográficos
Autores principales: Weiand, Matthias, Ballmaier, Paula, Niemietz, Christoph, Schmidt, Hartmut, Zibert, Andree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294256/
https://www.ncbi.nlm.nih.gov/pubmed/35865272
http://dx.doi.org/10.1016/j.bbrep.2022.101308