Ceftriaxone as a Novel Therapeutic Agent for Hyperglutamatergic States: Bridging the Gap Between Preclinical Results and Clinical Translation

Dysregulation of glutamate homeostasis is a well-established core feature of neuropsychiatric disorders. Extracellular glutamate concentration is regulated by glutamate transporter 1 (GLT-1). The discovery of a beta-lactam antibiotic, ceftriaxone (CEF), as a safe compound with unique ability to upre...

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Detalles Bibliográficos
Autores principales: Abulseoud, Osama A., Alasmari, Fawaz, Hussein, Abdelaziz M., Sari, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294323/
https://www.ncbi.nlm.nih.gov/pubmed/35864981
http://dx.doi.org/10.3389/fnins.2022.841036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294323/
https://www.ncbi.nlm.nih.gov/pubmed/35864981
http://dx.doi.org/10.3389/fnins.2022.841036

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