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Effects of Mexiletine on a Race-specific Mutation in Na(v)1.5 Associated With Long QT Syndrome
The voltage-gated sodium channel Na(v)1.5 plays an essential role in the generation and propagation of action potential in cardiomyocytes. Mutations in Na(v)1.5 have been associated with LQT syndrome, Brugada syndrome, and sudden arrhythmia death syndrome. Genetic studies showed that Na(v)1.5 mutati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294368/ https://www.ncbi.nlm.nih.gov/pubmed/35864896 http://dx.doi.org/10.3389/fphys.2022.904664 |