A ROCK1 Inhibitior Fasudil Alleviates Cardiomyocyte Apoptosis in Diabetic Cardiomyopathy by Inhibiting Mitochondrial Fission in a Type 2 Diabetes Mouse Model

Diabetes mellitus (DM) often involves cardiovascular complications; however, treatment regimens are limited. ROCK1 (rho-associated coiled-coil containing protein kinase 1) serves as a pathological factor in several diabetic complications. Herein, we aimed to explore the effect of Fasudil (a ROCK1 in...

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Detalles Bibliográficos
Autores principales: Fan, Xinhui, Li, Xiaoxing, Liu, Huiruo, Xu, Feng, Ji, Xiaoping, Chen, Yuguo, Li, Chuanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294374/
https://www.ncbi.nlm.nih.gov/pubmed/35865967
http://dx.doi.org/10.3389/fphar.2022.892643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294374/
https://www.ncbi.nlm.nih.gov/pubmed/35865967
http://dx.doi.org/10.3389/fphar.2022.892643

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