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Activation of 2‐oxoglutarate receptor 1 (OXGR1) by α‐ketoglutarate (αKG) does not detectably stimulate Pendrin‐mediated anion exchange in Xenopus oocytes

SLC26A4/Pendrin is the major electroneutral Cl(−)/HCO(3) (−) exchanger of the apical membrane of the Type B intercalated cell (IC) of the connecting segment (CNT) and cortical collecting duct (CCD). Pendrin mediates both base secretion in response to systemic base load and Cl(−) reabsorption in resp...

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Detalles Bibliográficos
Autores principales: Heneghan, John F., Majmundar, Amar J., Rivera, Alicia, Wohlgemuth, Jay G., Dlott, Jeffrey S., Snyder, L. Michael, Hildebrandt, Friedhelm, Alper, Seth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294391/
https://www.ncbi.nlm.nih.gov/pubmed/35851763
http://dx.doi.org/10.14814/phy2.15362