Systematic evaluation of cell-type deconvolution pipelines for sequencing-based bulk DNA methylomes

DNA methylation analysis by sequencing is becoming increasingly popular, yielding methylomes at single-base pair and single-molecule resolution. It has tremendous potential for cell-type heterogeneity analysis using intrinsic read-level information. Although diverse deconvolution methods were develo...

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Detalles Bibliográficos
Autores principales: Jeong, Yunhee, de Andrade e Sousa, Lisa Barros, Thalmeier, Dominik, Toth, Reka, Ganslmeier, Marlene, Breuer, Kersten, Plass, Christoph, Lutsik, Pavlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294431/
https://www.ncbi.nlm.nih.gov/pubmed/35794707
http://dx.doi.org/10.1093/bib/bbac248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294431/
https://www.ncbi.nlm.nih.gov/pubmed/35794707
http://dx.doi.org/10.1093/bib/bbac248

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