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Are mRNA based transcriptomic signatures ready for diagnosing tuberculosis in the clinic? - A review of evidence and the technological landscape

Advances in discovery and validation of diagnostic, prognostic and treatment-monitoring transcriptomic signatures of tuberculosis (TB) disease could accelerate the goal to end TB. We conducted a review to evaluate whether mRNA transcriptomics technologies are sufficiently mature to develop accurate...

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Detalles Bibliográficos
Autores principales: Hamada, Yohhei, Penn-Nicholson, Adam, Krishnan, Sriram, Cirillo, Daniela Maria, Matteelli, Alberto, Wyss, Romain, Denkinger, Claudia M., Rangaka, Molebogeng X., Ruhwald, Morten, Schumacher, Samuel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294474/
https://www.ncbi.nlm.nih.gov/pubmed/35850011
http://dx.doi.org/10.1016/j.ebiom.2022.104174