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HIV protease inhibitor nelfinavir is a potent drug candidate against echinococcosis by targeting Ddi1-like protein

BACKGROUND: Alveolar echinococcosis (AE), which is caused by larval Echinococcus multilocularis, is one of the world's most dangerous neglected diseases. Currently, no fully effective treatments are available to cure this disease. METHODS: In vitro protoscolicidal assay along with in vivo murin...

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Detalles Bibliográficos
Autores principales: Liu, Zhongli, Guo, Xiaola, Guo, Aijiang, Zhang, Shengying, Zou, Yang, Wang, Yugui, Li, Xiaolu, He, Wei, Pu, Lixia, Zhang, Shaohua, Zeng, Qiaoying, Cai, Xuepeng, Wang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294487/
https://www.ncbi.nlm.nih.gov/pubmed/35843171
http://dx.doi.org/10.1016/j.ebiom.2022.104177