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HIV protease inhibitor nelfinavir is a potent drug candidate against echinococcosis by targeting Ddi1-like protein
BACKGROUND: Alveolar echinococcosis (AE), which is caused by larval Echinococcus multilocularis, is one of the world's most dangerous neglected diseases. Currently, no fully effective treatments are available to cure this disease. METHODS: In vitro protoscolicidal assay along with in vivo murin...
Autores principales: | Liu, Zhongli, Guo, Xiaola, Guo, Aijiang, Zhang, Shengying, Zou, Yang, Wang, Yugui, Li, Xiaolu, He, Wei, Pu, Lixia, Zhang, Shaohua, Zeng, Qiaoying, Cai, Xuepeng, Wang, Shuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294487/ https://www.ncbi.nlm.nih.gov/pubmed/35843171 http://dx.doi.org/10.1016/j.ebiom.2022.104177 |
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