Impact of Intrahost NS5 Nucleotide Variations on Dengue Virus Replication

Due to the nature of RNA viruses, their high mutation rates produce a population of closely related but genetically diverse viruses, termed quasispecies. To determine the role of quasispecies in DENV disease severity, 22 isolates (10 from mild cases, 12 from fatal cases) were obtained, amplified, an...

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Detalles Bibliográficos
Autores principales: Cheng, Dayna, Huang, Sheng-Wen, Chin, Wei-Xin, Hung, Su-Jhen, Tsai, Huey-Pin, Chu, Justin Jang Hann, Chao, Chiao-Hsuan, Wang, Jen-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294511/
https://www.ncbi.nlm.nih.gov/pubmed/35865937
http://dx.doi.org/10.3389/fmicb.2022.894200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294511/
https://www.ncbi.nlm.nih.gov/pubmed/35865937
http://dx.doi.org/10.3389/fmicb.2022.894200

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