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Evaluation of the Effect of Gene Duplication by Genome Editing on Drug Resistance in Plasmodium falciparum

The emergence and spread of drug-resistant Plasmodium falciparum have compromised antimalarial efficacy and threatened the global malaria elimination campaign using artemisinin combination therapies. The impacts of amino acid substitutions in antimalarial drug resistance-associated genes on drug sus...

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Detalles Bibliográficos
Autores principales: Kubota, Rie, Ishino, Tomoko, Iwanaga, Shiroh, Shinzawa, Naoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9294729/
https://www.ncbi.nlm.nih.gov/pubmed/35865822
http://dx.doi.org/10.3389/fcimb.2022.915656