Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis

Inhibiting cancer metabolism via glutaminase (GAC) is a promising strategy to disrupt tumor progression. However, mechanism regarding GAC acetylation remains mostly unknown. In this study, we demonstrate that lysine acetylation is a vital post-translational modification that inhibits GAC activity in...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Lu, Zhuo, Han, Tianyu, Wang, Yanan, Gan, Mingxi, Wang, Jian-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295053/
https://www.ncbi.nlm.nih.gov/pubmed/35864951
http://dx.doi.org/10.7150/ijbs.69882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295053/
https://www.ncbi.nlm.nih.gov/pubmed/35864951
http://dx.doi.org/10.7150/ijbs.69882

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