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Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis
Inhibiting cancer metabolism via glutaminase (GAC) is a promising strategy to disrupt tumor progression. However, mechanism regarding GAC acetylation remains mostly unknown. In this study, we demonstrate that lysine acetylation is a vital post-translational modification that inhibits GAC activity in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295053/ https://www.ncbi.nlm.nih.gov/pubmed/35864951 http://dx.doi.org/10.7150/ijbs.69882 |