PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis

Previous studies have demonstrated the in vitro oncogenic role of protein arginine methyltransferase 5 (PRMT5) in gastric cancer cell lines. The in vivo function of PRMT5 in gastric tumorigenesis, however, is still unexplored. Here, we showed that Prmt5 deletion in mouse gastric epithelium resulted...

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Detalles Bibliográficos
Autores principales: Tang, Yuling, Dong, Lei, Zhang, Chong, Li, Xiubin, Li, Rongyu, Lin, Huisang, Qi, Yini, Tang, Mingchuan, Peng, Yanli, Liu, Chuan, Zhou, Jian, Hou, Ning, Liu, Wenjia, Yang, Guan, Yang, Xiao, Teng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295066/
https://www.ncbi.nlm.nih.gov/pubmed/35864961
http://dx.doi.org/10.7150/ijbs.71581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295066/
https://www.ncbi.nlm.nih.gov/pubmed/35864961
http://dx.doi.org/10.7150/ijbs.71581

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