PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis

Previous studies have demonstrated the in vitro oncogenic role of protein arginine methyltransferase 5 (PRMT5) in gastric cancer cell lines. The in vivo function of PRMT5 in gastric tumorigenesis, however, is still unexplored. Here, we showed that Prmt5 deletion in mouse gastric epithelium resulted...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yuling, Dong, Lei, Zhang, Chong, Li, Xiubin, Li, Rongyu, Lin, Huisang, Qi, Yini, Tang, Mingchuan, Peng, Yanli, Liu, Chuan, Zhou, Jian, Hou, Ning, Liu, Wenjia, Yang, Guan, Yang, Xiao, Teng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295066/
https://www.ncbi.nlm.nih.gov/pubmed/35864961
http://dx.doi.org/10.7150/ijbs.71581

Ejemplares similares

Ejemplares similares