Scaled up and telescoped synthesis of propofol under continuous-flow conditions

Herein we report a machine-assisted and scaled-up synthesis of propofol, a short-acting drug used in procedural sedation, which is extensively in demand during this COVID-19 pandemic. The continuous-flow protocol proved to be efficient, with great potential for industrial translation, reaching a pro...

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Detalles Bibliográficos
Autores principales: Martins, Guilherme M., Magalhães, Maria F. A., Brocksom, Timothy J., Bagnato, Vanderlei S., de Oliveira, Kleber T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Full Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295094/
https://www.ncbi.nlm.nih.gov/pubmed/35873601
http://dx.doi.org/10.1007/s41981-022-00234-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295094/
https://www.ncbi.nlm.nih.gov/pubmed/35873601
http://dx.doi.org/10.1007/s41981-022-00234-0

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