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EccDNAs are apoptotic products with high innate immunostimulatory activity

Extrachromosomal circular DNA elements (EccDNAs) have been described in the literature for several decades, and are known for their broad existence across different species(1,2). However, their biogenesis, and functions are largely unknown. By developing a new circular DNA enrichment method, here we...

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Detalles Bibliográficos
Autores principales: Wang, Yuangao, Wang, Meng, Djekidel, Mohamed Nadhir, Chen, Huan, Liu, Di, Alt, Fred, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295135/
https://www.ncbi.nlm.nih.gov/pubmed/34671165
http://dx.doi.org/10.1038/s41586-021-04009-w