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Identification of Macrolepiota procera extract as a novel G6PD inhibitor for the treatment of lung cancer

Tumor metabolism, an emerging hallmark of cancer, is characterized by aberrant expression of enzymes from various metabolic pathways including glycolysis and PPP (pentose phosphate pathway). Glucose 6 phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD), oxidative carboxylases...

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Detalles Bibliográficos
Autores principales: Zara, Rabia, Rasul, Azhar, Sultana, Tayyaba, Jabeen, Farhat, Selamoglu, Zeliha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295138/
https://www.ncbi.nlm.nih.gov/pubmed/35865797
http://dx.doi.org/10.1016/j.sjbs.2022.02.018