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Switchable Control of Scaffold Protein Activity via Engineered Phosphoregulated Autoinhibition

[Image: see text] Scaffold proteins operate as organizing hubs to enable high-fidelity signaling, fulfilling crucial roles in the regulation of cellular processes. Bottom-up construction of controllable scaffolding platforms is attractive for the implementation of regulatory processes in synthetic b...

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Detalles Bibliográficos
Autores principales: Hazegh Nikroo, Arjan, Lemmens, Lenne J. M., Wezeman, Tim, Ottmann, Christian, Merkx, Maarten, Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295147/
https://www.ncbi.nlm.nih.gov/pubmed/35765959
http://dx.doi.org/10.1021/acssynbio.2c00122