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Switchable Control of Scaffold Protein Activity via Engineered Phosphoregulated Autoinhibition
[Image: see text] Scaffold proteins operate as organizing hubs to enable high-fidelity signaling, fulfilling crucial roles in the regulation of cellular processes. Bottom-up construction of controllable scaffolding platforms is attractive for the implementation of regulatory processes in synthetic b...
Autores principales: | Hazegh Nikroo, Arjan, Lemmens, Lenne J. M., Wezeman, Tim, Ottmann, Christian, Merkx, Maarten, Brunsveld, Luc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295147/ https://www.ncbi.nlm.nih.gov/pubmed/35765959 http://dx.doi.org/10.1021/acssynbio.2c00122 |
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