Aquaporin 9 induction in human iPSC‐derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency

BACKGROUND AND AIMS: Patient‐derived human‐induced pluripotent stem cells (hiPSCs) differentiated into hepatocytes (hiPSC‐Heps) have facilitated the study of rare genetic liver diseases. Here, we aimed to establish an in vitro liver disease model of the urea cycle disorder ornithine transcarbamylase...

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Detalles Bibliográficos
Autores principales: Laemmle, Alexander, Poms, Martin, Hsu, Bernadette, Borsuk, Mariia, Rüfenacht, Véronique, Robinson, Joshua, Sadowski, Martin C., Nuoffer, Jean‐Marc, Häberle, Johannes, Willenbring, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295321/
https://www.ncbi.nlm.nih.gov/pubmed/34786702
http://dx.doi.org/10.1002/hep.32247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295321/
https://www.ncbi.nlm.nih.gov/pubmed/34786702
http://dx.doi.org/10.1002/hep.32247

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